Home Dental Radiology Antiplaque and antigingivitis efficacy of cetylpyridinium chloride with zinc lactate compared with essential oil mouthrinses

Antiplaque and antigingivitis efficacy of cetylpyridinium chloride with zinc lactate compared with essential oil mouthrinses

by adminjay


Background

The authors of this study aimed to evaluate the clinical antiplaque and antigingivitis
effects of 3 oral hygiene regimens: toothbrushing with standard fluoride toothpaste
and manual toothbrush and using a mouthrinse containing cetylpyridinium chloride,
zinc lactate, and fluoride (CPC + Zn + F) in an alcohol-free base; toothbrushing with
standard fluoride toothpaste and manual toothbrush and using a mouthrinse containing
essential oils (EO) in an alcohol-free base; and toothbrushing with manual toothbrush
and standard fluoride toothpaste and manual toothbrush (control).

Methods

The participants (N = 120) were randomly assigned to study groups and followed the
assigned regimens twice daily for 6 weeks. The participants were examined by a calibrated
examiner for the Quigley-Hein plaque index (Turesky modification) and Löe-Silness
gingival index at baseline, week 4, and week 6. Statistical analyses were performed
separately for plaque and gingival indexes by means of analysis of variance, paired

t test, and analysis of covariance (α = 0.05).

Results

At week 4, the CPC + Zn + F group presented additional reductions in dental plaque
compared with EO and control groups of (21.4% [
P < .001] and 31.4% [
P < .001], respectively). After 6 weeks, these values were 26.7% (
P < .001) and 44.8% (
P < .001), respectively. For Löe-Silness gingival index, additional reduction in the
CPC + Zn + F group compared with EO were 10.6% (
P < .001) and 13.7% (
P < .001) at 4 and 6 weeks, respectively. Compared with control, these reductions were
13.6% (
P < .001) and 17.8% (
P < .001), respectively.

Conclusions

The regimen including a mouthrinse containing CPC + Zn + F presented higher antiplaque
and antigingivitis effects than EO and control regimens.

Practical Implications

A mouthrinse containing CPC + Zn + F is an effective protocol for the control of dental
plaque and gingivitis.



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