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Dental implants in patients seropositive for HIV

by adminjay


Background and Overview

Patients seropositive HIV and AIDS represent a group of patients who experience longer
longevity at the expense of effective therapies for infection control and related
opportunistic diseases. However, the prolonged use of these drugs is often associated
with adverse events, which theoretically may influence dental management and the long-term
stability of dental implants. The objective of this study was to prospectively evaluate
a group of HIV-positive people from a previous study who had received dental implants
for 12 years after oral rehabilitation and functional loading.

Case Description

Nine patients with a total of 18 implants participated in this study. Viral load was
undetectable in 8 patients, with 1 who had 48 copies/milliliter. The cluster of differentiation
4 T lymphocyte count ranged from 227 through 1,000 cells/cubic millimeter, mean (standard
deviation [SD]) 564 (271.13) cells/mm
3. Five of the 9 (55.5%) patients had visible plaque, and 5 (55.5%) had bleeding on
probing with no implant mobility. Radiographs obtained at 6 months, 12 months, and
12 years of functional loading showed mean (SD) marginal bone losses of 0.32 (0.23)
mm, 0.37 (0.23) mm, and 2.43 (1.48), respectively.

Conclusion and Practical Implications

These results suggest that dental implant treatment in HIV-positive patients achieved
long-term survival, with a success rate comparable with that observed in healthy patients,
indicating that implant rehabilitation is not a contraindication for HIV-positive
patients.



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