Home Pediatric Dentistry Iranian early childhood dental caries: a comprehensive systematic review and meta-analysis of prevalence and associated risk factors

Iranian early childhood dental caries: a comprehensive systematic review and meta-analysis of prevalence and associated risk factors

by adminjay


  • Nematollahi H, Mehrabkhani M, Sheykhani M. Assessing the relationship between diet and prevalence of early childhood caries in Birjand preschool children. J Dent. 2007;8:70–85.


    Google Scholar
     

  • Wagle M, D’Antonio F, Reierth E, Basnet P, Trovik TA, Orsini G, et al. Dental caries and preterm birth: a systematic review and meta-analysis. BMJ open. 2018;8:e018556.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Broumand S, Sharififar S, Alikhani S. The study of caries free indicator of milk teeth in children age 3–6 at dare care center affiliated to health centers of Army. 2006:828–835.

  • Hallett KB, O’Rourke PK. Pattern and severity of early childhood caries. Community Dent Oral Epidemiol. 2006;34:25–35.

    Article 
    PubMed 

    Google Scholar
     

  • Bayat Movahed S, Samadzadeh H, Ziyarati L, Memory N, Khosravi R, Sadr Eshkevari P. Oral health of Iranian children in 2004: a national pathfinder survey of dental caries and treatment needs. EMHJ-East Mediterranean Health J. 2011;17:243–9.

    Article 
    CAS 

    Google Scholar
     

  • World Health Organization Oral Health Surveys‐Basic Methods. Geneva: World Health Organization. 1997.

  • Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. bmj. 2021;372.

  • Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group* t. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151:264–9.

    Article 
    PubMed 

    Google Scholar
     

  • Esmaeilikia M, Gholami-Parizad E, Ghazanfari Z, Abedzadeh MS, Roozegar MA. Investigation of oral health status (DMFT-index) among 3-6 years old children in ilam (Western Iran), 2015. Res J Pharm Technol. 2020;13:1876–80.


    Google Scholar
     

  • Poureslami H, Enhesari A, Salari Z, Sharifi H, Poureslami P. Is there association between severe early childhood caries and weight at 25-28 weeks of fetal life? A longitudinal pilot study. J Oral Health Oral Epidemiol. 2016;5:40–5.


    Google Scholar
     

  • Mojarad F, Fazlollahifar S, Poorolajal J, Hajilooi M. Effect of alpha amylase on early childhood caries: a matched case-control study. Brazilian Dental. Science. 2013;16:41–5.


    Google Scholar
     

  • Bafti LS, Hashemipour MA, Poureslami H, Hoseinian Z. Relationship between body mass index and tooth decay in a population of 3–6-year-old children in Iran. Int J Dentistry. 2015;2015.

  • Mehrabkhani M, Ajami B, Khademi M, Arastoo S. Evaluating risk factors of dental caries in children under 6-years-old supported by Welfare Organization of Mashhad in 2012. J Mashhad Dent Sch. 2014;38:257–66.


    Google Scholar
     

  • Sistani MMN, Hataminia Z, Hajiahmadi M, Khodadadi E. Nine years’ trend of dental caries and severe early childhood caries among 3–6-year-old children in Babol. North Iran Electron Physician. 2017;9:4683.

    Article 

    Google Scholar
     

  • Ghasempour M, Hajian K, Moazzezi Z, Zovvar M. Relationship between BMI and dental caries index in preschool children in Babol. مجله دانشکده دندانپزشکی اصفهان. 2011:280-7.

  • Ghandahari-Motlagh M, Zeraati H. Dental health status in 3-5 year old kindergarten children in Tehran-Iran in 2003. Front Dent. 2005:18–20.

  • MALEK MT, Hossienian Z, Bakhteyar M. The association of body mass index with dental caries in an Iranian sample of children. 2012:29–35.

  • Parsaie Z, Rezaie P, Azimi N, Mohammadi N. Relationship between salivary alpha-amylase enzyme activity, anthropometric indices, dietary habits, and early childhood dental caries. Int J Dent. (2022);2022:2617197.

  • Mirahmadizadeh A, Zahmatkesh S, Mahizadeh H, Mokhtari AM, Vali M, Abedinzade A. Dental caries experience and its relationship to demographic factors in 2- to 6-year-old children in Fars-Iran in 2018. Int J Dent Hyg. 2022;20:643–9.

    Article 
    PubMed 

    Google Scholar
     

  • Jamshidi M, Sistani MMN, Boushehri N, Hamzeh M. Prevalence of early childhood caries and the related factors among 3-5-Year-Old children in Babol, Iran. J Dent. 2022;23:137.


    Google Scholar
     

  • Abedizadeh H, Faramarzi M, Khafri S, Qujeq Q, Ahangary M, Ghasempour M. The association between the salivary cortisol level of mothers, children’s temperament, and early childhood caries. J Indian Soc Pedodontics Prev Dent. 2021;39:196–201.

    Article 

    Google Scholar
     

  • HEMMATI S, Kermani P, Cherati JY, Hali H. The relationship between severe early childhood caries and BMI in 3-6-Year-Old Children. J Mashhad Dent Sch. 2021;45:188–95.


    Google Scholar
     

  • Zeinabadi MS, Hashemian SHOI, Ghorbani R, Tosan F, Ghaneei F, Ameli N. Early childhood caries and its association with socio-economic risk factors. Koomesh 2020;22:269–74.

    Article 

    Google Scholar
     

  • Yazdani R, Mohebbi SZ, Fazli M, Peighoun M. Evaluation of protective factors in caries free preschool children: a case-control study. BMC Oral Health. 2020;20:177.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Amirabadi F, Saffari Y. Evaluating the relationship between parental dental anxiety and early childhood caries. Int J Pediatr. 2020;8:11393–401.


    Google Scholar
     

  • Pourhoseingholi A, Baghban AA, Baghestani AR, Ghasemi E, Safavi SMR. Zero inflated binomial model for prognosis of the risk factors associated with dmft index in children aged 5 – 6 years in Tehran. Iranian J Pediatr. 2018;28.

  • Mousavi M, Kharrazifard MJ, Yekaninejad MS, Rahimi Foroushani A. Effect of anthropometric, socioeconomic, and behavioral factors on early childhood dental caries in Tehran: a structural equations modeling approach. J Iranian Dent Assoc. 2017;29:158–67.

    Article 

    Google Scholar
     

  • Mortazavi S, Enshaei Z, Farajzadegan Z. Development of caries risk assessment tool for iranian preschoolers: a primary validation study. Int J Prevent Med. 2017;8.

  • Khani-Varzegani F, Erfanparast L, Asghari-Jafarabadi M, Shokravi M, Azabdaftari F, Parto M, et al. Early occurrence of childhood dental caries among low literate families. BMC Res Notes. 2017;10:366.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Panahi R, Zadeh AA, Javanmardi E, Soleymanzadeh R, Moradi M, Varo OZ, et al. Prevalence of early childhood dental caries and some related factors among 3-6 year-old children in Marivan – 2016. J Health Field. 2019;7:18–25.


    Google Scholar
     

  • Ahsaie MG, Deghatipour M, Fazeli KS, Bastani P, Ehdaivand F, Ghorbani Z. Dental decay and associated factors in Iranian three years old children. J Dent Sch. 2017;35:104–13.


    Google Scholar
     

  • Toutouni H, Mohammad, Nokhostin R, Amaechi BT, Zafarmand AH. The prevalence of early childhood caries among 24 to 36 months old children of iran: using the Novel ICDAS-II Method. J Dent Shiraz Univ Med Sci. 2015;16:362–70.


    Google Scholar
     

  • Vejdani J, Hadipoor Z, Leyli EKN. Risk factors for severe early childhood caries in 2-3-year-old children in Rasht. J Dentomaxillofacil Radiol Pathol Surg. 2014;2:15–22.

    Article 

    Google Scholar
     

  • Aminabadi NA, Ghoreishizadeh A, Ghoreishizadeh M, Oskouei SG, Ghojazadeh M. Can child temperament be related to early childhood caries? Caries Res. 2014;48:3–12.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Nabipour AR, Azvar K, Zolala F, Ahmadinia H, Soltani Z.The prevalence of early dental caries and its contributing factors among 3-6-Year-Old children in Varamin/Iran. Health Dev J. 2013;2:12–21.


    Google Scholar
     

  • Moulana Z, Pour MG, Pour FA, Elmi M, Shaker PB.The frequency of Streptococcus Mutans and Lactobacillus spp.in 3-5-year- old Children with and without Dental Caries. Med Lab J. 2013;7:29–34.


    Google Scholar
     

  • Poureslami H, Bafti LS, Hashemi Z, Salari Z. Comparison of occurrence of early childhood caries in two groups of children delivered by cesarean section and normal birth: a longitudinal study. J Compr Pediatr. 2012;3:77.

    Article 

    Google Scholar
     

  • Toomarian L, Sattari M, Hashemi N, Tadayon N, Baghban AA. Comparison of Neutrophil Apoptosis, α-Defensins and Calprotectin in children with and without severe early childhood caries. Iranian J Immunol. 2011;8:11–9.

    CAS 

    Google Scholar
     

  • Ghasempour M, Sefidgar SAA, Eyzadian H, Gharakhani S. Prevalence of candida albicans in dental plaque and caries lesion of early childhood caries (ECC) according to sampling site. Caspian. J Intern Med. 2011;2:304–8.


    Google Scholar
     

  • Amanlou M, Jafari S, Afzalianmand N, Omrany ZB, Farsam H, Nabati F, et al. Association of saliva fluoride level and socioeconomic factors with dental caries in 3-6 years old children in Tehran-Iran. Iranian J Pharm Res. 2011;10:159–66.


    Google Scholar
     

  • Jabbarifar SE, Ahmady N, Sahafian SAR, Samei F, Soheillipour S. Association of parental stress and early childhood caries. Dent Res J. 2009;6:65.


    Google Scholar
     

  • Mazhari F, Talebi M, Zoghi M. Prevalence of early childhood caries and its risk factors in 6-60 months old Children in Quchan. Dent Res J. 2008;4:96.


    Google Scholar
     

  • Koopaie M, Salamati M, Montazeri R, Davoudi M, Kolahdooz S. Salivary cystatin S levels in children with early childhood caries in comparison with caries-free children; statistical analysis and machine learning. BMC Oral Health. 2021;21:650.

  • Janeshin A, Sabet AH, Mirdamadi S. Evaluation of the effect of problematic eating behavior on early childhood caries in children aged 3 to 6 years. Iranian J Pediatr Dent 2021;16:70–80.


    Google Scholar
     

  • Mehrabkhani M, Nematy M, Movahed T, ASHOFTE BS, Mortazavi S. EVALUATION OF THE RELATIONSHIP BETWEEN FOOD PATTERNS AND EARLY CHILDHOOD CARIES IN 3-6 YEAR-OLD CHILDREN IN MASHHAD KINDERGARTENS. 2016:581–593.

  • Porhashemi J, Garshasby KG, Nahvi A. Relationship between sever early childhood caries and BMI in 2-4-Year-Old Children in Tehran Kindergartens. J Mazandaran Univ Med Sci. 2016;26:197–201.


    Google Scholar
     

  • Mehrabkhani HN, Mm S. Assessing the relationship between diet and prevalence of early childhood caries in Birjand Preschool Children. J Dent Shiraz Univ Med Sci. 2007;8:70.


    Google Scholar
     

  • Poureslami H, Sharifi M, Vahedi M, Sabouri S, Poureslami P, Satarzadeh N, et al. Evaluation of relationship between sever early childhood caries and breast Milk’s Lactose among 12- to 24-month-old Children. J Dent Shiraz Univ Med Sci. 2022;23:410–3.


    Google Scholar
     

  • Sharifi M, Pourseyedi A, Nejad JH, Aftabi R, Hatami N, Poureslami H.The relationship between weaning method and its time and severe early childhood caries. Prevent Care Nurs Midwifery J. 2021;11:40–5.

    Article 

    Google Scholar
     

  • Pahlevani Z, Eghbalian F, Esfehani FM, Chitgar Z. Evaluation of the incidence and pattern of early childhood dental caries and effective factors on 2-6 year old children in Hamedan in 2006. Feyz 2008;12:81.


    Google Scholar
     

  • Bahrololoumi Z, Soleymani A, Zandi H, Dastjerdi F, Rashidi M, Aghelinejad S. Evaluating the effect of enviromental factors and early childhood caries on salivary Streptococcus Mutans Count in 3-5 Year Old Children in Yazd. Tolooe Behdasht. 2017;15:23–34.


    Google Scholar
     

  • Ghasempour M, Rajabnia R, Irannejad A, Hamzeh M, Ferdosi E, Bagheri M. Frequency, biofilm formation and acid susceptibility of streptococcus mutans and streptococcus sobrinus in saliva of preschool children with different levels of caries activity. Dent Res J. 2013;10:440–5.


    Google Scholar
     

  • Jiang R, Yu J, Islam R, Li X, Nie E. Dental caries prevention knowledge, attitudes, and practice among patients at a University Hospital in Guangzhou, China. Medicina. 2023;59:1559.

  • Saikia A, Aarthi J, Muthu MS, Patil SS, Anthonappa RP, Walia T, et al. Sustainable development goals and ending ECC as a public health crisis. Front Public Health. 2022;10:931243.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Devan I, Ramanarayanan V, Janakiram C. Prevalence of early childhood caries in India: a systematic review and meta-analysis. Indian J Public Health. 2022;66:S3–S11.

    Article 
    PubMed 

    Google Scholar
     

  • Abdelrahman M, Hsu KL, Melo MA, Dhar V, Tinanoff N. Mapping evidence on early childhood caries prevalence: complexity of Worldwide Data Reporting. Int J Clin Pediatr Dent. 2021;14:1–7.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Malinowski K, Majewski M, Kostrzewska P, Całkosiński A. Early childhood caries–literature review on risk factors, prevalence and prevention. Medycyna Ogólna i Nauki o Zdrowiu. 2021;27:244.

  • Uribe SE, Innes N, Maldupa I. The global prevalence of early childhood caries: a systematic review with meta‐analysis using the WHO diagnostic criteria. Int J Paediatr Dent. 2021;31:817–30.

    Article 
    PubMed 

    Google Scholar
     

  • Anil S, Anand PS. Early childhood caries: prevalence, risk factors, and prevention. Front Pediatr. 2017;5:157.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Peltzer K, Mongkolchati A. Severe early childhood caries and social determinants in three-year-old children from Northern Thailand: a birth cohort study. BMC Oral Health. 2015;15:1–7.

    Article 

    Google Scholar
     

  • Zhou Y, Lin H, Lo E, Wong M. Risk indicators for early childhood caries in 2‐year‐old children in southern China. Aust Dent J. 2011;56:33–9.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Feldens C, Giugliani E, Vigo Á, Vítolo M. Early feeding practices and severe early childhood caries in four-year-old children from southern Brazil: a birth cohort study. Caries Res. 2010;44:445–52.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Fisher-Owens SA, Gansky SA, Platt LJ, Weintraub JA, Soobader M-J, Bramlett MD, et al. Influences on children’s oral health: a conceptual model. Pediatrics 2007;120:e510–e20.

    Article 
    PubMed 

    Google Scholar
     

  • Greenaway ES, Leon J, Baker DP. Understanding the association between maternal education and use of health services in Ghana: exploring the role of health knowledge. J Biosoc Sci. 2012;44:733–47.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Li Y, Zhang Y, Yang R, Zhang Q, Zou J, Kang D. Associations of social and behavioural factors with early childhood caries in Xiamen city in China. Int J Paediatr Dent. 2011;21:103–11.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wulaerhan J, Abudureyimu A, Bao X-L, Zhao J. Risk determinants associated with early childhood caries in Uygur children: a preschool-based cross-sectional study. BMC Oral Health. 2014;14:1–8.

    Article 

    Google Scholar
     

  • Menon I, Nagarajappa R, Ramesh G, Tak M. Parental stress as a predictor of early childhood caries among preschool children in India. Int J Paediatr Dent. 2013;23:160–5.

    Article 
    PubMed 

    Google Scholar
     

  • Hui Bin S, Zhang W, Zhou XB. Risk factors associated with early childhood caries. Chin J Dent Res. 2017;20:97–104.


    Google Scholar
     

  • Bonanato K, Paiva S, Pordeus I, Ramos-Jorge M, Barbabela D, Allison P. Relationship between mothers’ sense of coherence and oral health status of preschool children. Caries Res. 2009;43:103–9.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Borges HC, Garbín CAS, Saliba O, Saliba NA, Moimaz SAS. Socio-behavioral factors influence prevalence and severity of dental caries in children with primary dentition. Brazilian Oral Res. 2012;26:564–70.

    Article 

    Google Scholar
     

  • Gao X, Di Wu I, Lo ECM, Chu CH, Hsu C-yS, Wong MCM. Validity of caries risk assessment programmes in preschool children. J Dent. 2013;41:787–95.

    Article 
    PubMed 

    Google Scholar
     

  • Prendergast MJ, Beal JF, Williams SA. The relationship between deprivation, ethnicity and dental health in 5-year-old children in Leeds, UK. Community Dent Health. 1997;14:18–21.

    CAS 
    PubMed 

    Google Scholar
     

  • Hooley M, Skouteris H, Boganin C, Satur J, Kilpatrick N. Parental influence and the development of dental caries in children aged 0–6 years: a systematic review of the literature. J Dent. 2012;40:873–85.

    Article 
    PubMed 

    Google Scholar
     

  • Drummond B, Meldrum A, Boyd D. Influence of dental care on children’s oral health and wellbeing. Br Dent J. 2013;214:E27–E.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Jamieson L, Luzzi L, Chrisopoulos S, Roberts R, Arrow P, Kularatna S, et al. Oral health, social and emotional well-being, and economic costs: protocol for the Second Australian National Child Oral Health Survey. JMIR Res Protoc. 2023;12:e52233.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Curtis B, Evans RW, Sbaraini A, Schwarz E. Geographic location and indirect costs as a barrier to dental treatment: a patient perspective. Aust Dent J. 2007;52:271–5.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Wigen TI, Wang NJ. Caries and background factors in Norwegian and immigrant 5‐year‐old children. Community Dent Oral Epidemiol. 2010;38:19–28.

    Article 
    PubMed 

    Google Scholar
     

  • Wigen TI, Skaret E, Wang NJ. Dental avoidance behaviour in parent and child as risk indicators for caries in 5‐year‐old children. Int J Paediatr Dent. 2009;19:431–7.

    Article 
    PubMed 

    Google Scholar
     

  • Qadri G, Nourallah A, Splieth CH. Early childhood caries and feeding practices in kindergarten children. Quintessence Int. 2012;43.

  • Slabšinskienė E, Milčiuvienė S, Narbutaitė J, Vasiliauskienė I, Andruškevičienė V, Bendoraitienė E-A, et al. Severe early childhood caries and behavioral risk factors among 3-year-old children in Lithuania. Medicina. 2010;46:135.

    Article 
    PubMed 

    Google Scholar
     

  • Shrikrishna Suprabha B, Shenoy R, Mahabala Karuna Y, Nayak AP, Rao A, D’Souza V. Dietary practices among children with early childhood caries and the associated factors: a qualitative study. Int J Paediatr Dent. 2022;32:176–84.

    Article 
    PubMed 

    Google Scholar
     

  • Parra-Coronel J, Astudillo-Neira D, Ortiz-Ulloa J. Early childhood caries and risk factors in young children of medium-low socioeconomic status, Ecuador. Rev Investig Salud Univ de Boyacá. 2020;7:52–70.

    Article 

    Google Scholar
     

  • Amer AI, Almohammadi KS, Al-Majed OS, Al Harbi SH, Aljohani RM, Sabri LM, et al. Stages, risk factors and prevention of early childhood caries. Int J Community Med Public Health. 2022;9:1.

    Article 

    Google Scholar
     

  • Zheng X, Cao CY, Cao SP, Ran Q, Wu SW, Guo ZL. The prevention of childhood dental caries in China. American. J Pediatr. 2020;6:228–33.


    Google Scholar
     

  • Soares RC, da Rosa SV, Moysés ST, Rocha JS, Bettega PVC, Werneck RI, et al. Methods for prevention of early childhood caries: Overview of systematic reviews. Int J Paediatr Dent. 2021;31:394–421.

    Article 
    PubMed 

    Google Scholar
     

  • Kawashita Y, Kitamura M, Saito T. Early childhood caries. Int J Dent. 2011;2011:725320.

  • Tham R, Bowatte G, Dharmage SC, Tan DJ, Lau MX, Dai X, et al. Breastfeeding and the risk of dental caries: a systematic review and meta‐analysis. Acta Paediatr. 2015;104:62–84.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Avila WM, Pordeus IA, Paiva SM, Martins CC. Breast and bottle feeding as risk factors for dental caries: a systematic review and meta-analysis. PloS ONE. 2015;10:e0142922.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Richards D. Breastfeeding up to 12 months of age not associated with increased risk of caries. Evid Based Dent. 2016;17:75–6.

    Article 
    PubMed 

    Google Scholar
     

  • Cui L, Li X, Tian Y, Bao J, Wang L, Xu D, et al. Breastfeeding and early childhood caries: a meta-analysis of observational studies. Asia Pac J Clin Nutr. 2017;26:867–80.

    PubMed 

    Google Scholar
     

  • Birungi N, Fadnes LT, Okullo I, Kasangaki A, Nankabirwa V, Ndeezi G, et al. Effect of breastfeeding promotion on early childhood caries and breastfeeding duration among 5 year old children in eastern Uganda: a cluster randomized trial. PloS ONE. 2015;10:e0125352.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Chaffee BW, Feldens CA, Vítolo MR. Association of long-duration breastfeeding and dental caries estimated with marginal structural models. Ann Epidemiol 2014;24:448–54.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Peres KG, Nascimento GG, Peres MA, Mittinty MN, Demarco FF, Santos IS, et al. Impact of prolonged breastfeeding on dental caries: a population-based birth cohort study. Pediatrics. 2017;140.

  • Boustedt K, Dahlgren J, Twetman S, Roswall J. Tooth brushing habits and prevalence of early childhood caries: a prospective cohort study. Eur Arch Paediatr Dent. 2020;21:155–9.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Majorana A, Cagetti MG, Bardellini E, Amadori F, Conti G, Strohmenger L, et al. Feeding and smoking habits as cumulative risk factors for early childhood caries in toddlers, after adjustment for several behavioral determinants: a retrospective study. BMC Pediatr. 2014;14:1–8.

    Article 

    Google Scholar
     

  • Mahjoub S, Ghasempour M, Mohammadi I. Salivary alkaline phosphatase activity and inorganic phosphorus concentration in children with different dental caries. J Babol Univ Med Sci. 2007;9:23–8.


    Google Scholar
     

  • Amrollahi N, Enshaei Z, Kavousi F. Salivary Malondialdehyde Level as a Lipid Peroxidation Marker in Early Childhood Caries. Iranian J Pediatr. 2021;31:5.

    Article 

    Google Scholar
     

  • Hutchison C. Can protective factors prevent caries in preschool children? Evid Based Dent. 2021;22:114–5.

    Article 
    PubMed 

    Google Scholar
     

  • Aliakbarpour F, Mahjoub S, Masrour-Roudsari J, Seyedmajidi S, Ghasempour M. Evaluation of salivary thiobarbituric acid reactive substances, total protein, and pH in children with various degrees of early childhood caries: a case–control study. Eur Arch Paediatr Dent. 2021;22:1095–9.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Bijani M, Mostafazadeh A, Motallebnejad M, Bijani A, Pourbagher R, Gharekhani S. Evaluation of the Level of Salivary sHLA-G in Children Aged 3-5 Years with or without Dental Caries. Int J Dent. 2020;2020:8870055.

  • Jalali MM, Faghih Habibi A, Ramezani H. Evaluation of the association between dental caries status and middle ear effusion in preschool children in Rasht City. Sci J Kurd Univ Med Sci. 2019;24:116–24.


    Google Scholar
     

  • Shamsaddin H, Jahanimoghadam F, Poureslami H, Haghdoost AA. The association between growth factors and blood factors with early childhood caries. J Oral Health Oral Epidemiol. 2018;6:196–202.


    Google Scholar
     

  • Poureslami H, Salari Z, Khajeh-Hasani R, Jokar S, Poureslami P. Evaluation of salivary glucose levels among children with early childhood caries compared to children with healthy teeth. J Oral Health Oral Epidemiol. 2018;7:16–20.


    Google Scholar
     

  • Bakhshaee M, Ashtiani S, Hossainzadeh M, Sehatbakhsh S, Najafi M, Salehi M. Allergic rhinitis and dental caries in preschool children. Dent Res J. 2017;14:376–81.

    Article 

    Google Scholar
     

  • Seyedmajidi M, Khodadadi E, Maliji G, Zaghian M, Bijani A. Neutrophil Count and Level of Interleukin-1β and Interleukin-8 in the Saliva of Three to Five Year Olds with and without Dental Caries. Front Dent. 2016;12:662–8.


    Google Scholar
     

  • Moslemi M, Sattari M, Kooshki F, Fotuhi F, Modarresi N, Sadrabad ZK, et al. Relationship of salivary lactoferrin and lysozyme concentrations with Early Childhood Caries. J Dent Res, Dent Clin, Dent Prospect. 2015;9:109–14.

    Article 

    Google Scholar
     

  • Malekafzali B, Sattari M, Keyvanfar S. Correlation between salivary Toll Like Receptor-2 concentration and early childhood caries. Iranian J Immunol. 2014;11:210.


    Google Scholar
     

  • Edalat A, Abbaszadeh M, Eesvandi M, Heidari A. The relationship of severe early childhood caries and body mass index in a Group of 3- to 6-year-old Children in Shiraz. J Dent, Shiraz Univ Med Sci. 2014;15:68–73.

    CAS 

    Google Scholar
     

  • Bagherian A, Sadeghi M. Association between dental caries and age-specific body mass index in preschool children of an Iranian population. Indian J Dent Res. 2013;24:66–70.

    Article 
    PubMed 

    Google Scholar
     

  • Sadeghi M, Darakhshan R, Bagherian A. Is there an association between early childhood caries and serum iron and serum ferritin levels? Dent Res J. 2012;9:294.

    CAS 

    Google Scholar
     

  • Bagherian A, Asadikaram G. Comparison of some salivary characteristics between children with and without early childhood caries. Indian J Dent Res. 2012;23:628–32.

    Article 
    PubMed 

    Google Scholar
     

  • Jabarifar SE, Ahmadi N, Hashemi D, Karami S. Relationship between early childhood caries and weight, height, body mass index and head circumferences in 3-5 year-old children in Kazeroun. J Isfahan Dent Sch. 2011;6:783.


    Google Scholar
     

  • POUR ESLAMI HR, Moshtaghi GH, Hori A, SHarifi MA, Ziaaddini H. Comparison of Salivary Secretory IgA in Caries-free Children and Children with Severe Early Childhood Caries. J Kerman Univ Med Sci. 2010;18:83–8.

  • Biria M, Sattari M, Golpayegani MV, Kooshki F. Association of salivary sCD14 concentration levels with early childhood caries. Iranian J Immunol. 2010;7:193.

    CAS 

    Google Scholar
     

  • Shahrabi M, Nikfarjam J, Alikhani A, Akhoundi N, Ashtiani M, Seraj B. A comparison of salivary calcium, phosphate, and alkaline phosphatase in children with severe, moderate caries, and caries free in Tehran’s kindergartens. J Indian Soc Pedodontics Prev Dent. 2008;26:74–7.

    Article 
    CAS 

    Google Scholar
     

  • Bagherian A, Nematollahi H, Afshari J, Moheghi N. Comparison of allele frequency for HLA-DR and HLA-DQ between patients with ECC and caries-free children. J Indian Soc Pedodontics Prev Dent. 2008;26:18–21.

    Article 
    CAS 

    Google Scholar
     

  • Bagherian A, Jafarzadeh A, Rezaeian M, Ahmadi S, Rezaity MT. Comparison of the salivary immunoglobulin concentration levels between children with early childhood caries and caries-free children. Iranian J Immunol. 2008;5:217–21.

    CAS 

    Google Scholar
     

  • Mokhtari S, Mokhtari S, Sabour S, Hosseini Z. Evaluation of the relationship between dental caries and dermatoglyphics in 3 to 6-Year-Old Iranian children. Niger J Clin Pract. 2021;24:193–8.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Arefi AH, Shamsaddin H, Balvardi M, Poureslami H, Danesh M, Sayadizadeh M. Evaluation of parents’ views about etiologic factors of severe early childhood caries: a qualitative study. J Dent Res, Dent Clin, Dent Prospect. 2019;13:43–50.

    Article 

    Google Scholar
     

  • Mohebbi SZ, Virtanen JI, Vahid-Golpayegani M, Vehkalahti MM. Feeding habits as determinants of early childhood caries in a population where prolonged breastfeeding is the norm. Community Dent Oral Epidemiol. 2008;36:363–9.

    Article 
    CAS 
    PubMed 

    Google Scholar
     



  • Source link

    Related Articles