The coagulopathy of chronic liver disease.
Surv Anesthesiol. 2012; 365: 147-156
An imbalance of pro- vs anti-coagulation factors in plasma from patients with cirrhosis.
Gastroenterology. 2009; 137: 2105-2111
Changing concepts of cirrhotic coagulopathy.
Am J Gastroenterol. 2017; 112: 274-281
Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions.
Cardiovasc Ther. 2010; 28: e72-e91
Bleeding risk with invasive procedures in patients with cirrhosis and coagulopathy.
Curr Gastroenterol Rep. 2017; 19: 45
Hemostasis and thrombosis in patients with liver disease: the ups and downs.
J Hepatol. 2020; 53: 362-371
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement.
PLoS Med. 2009; 6e1000097
Incidence of bleeding during oral surgery in patients with liver cirrhosis: a systematic review.
The Joanna Briggs Institute Reviewers’ Manual 2015: Methodology for JBI Umbrella Reviews.
Joanne Briggs Institute,
Adelaide, South Australia, Australia2015
Local hemostasis after tooth extraction in patients with abnormal hemostatic function: use of human fibrinogen concentrate.
Haemostasis. 1985; 15: 402-404
Bleeding during and after dental extractions in patients with liver cirrhosis.
Int J Oral Maxillofac Surg. 2018; 47: 1543-1549
Postoperative bleeding after dental extraction in liver pretransplant patients.
J Oral Maxillofac Surg. 2012; 70: 490-495
Dental postoperative bleeding complications in patients with suspected and documented liver disease.
Oral Dis. 2012; 18: 661-666
Long-term postoperative bleeding after dentoalveolar surgery in the pretransplant liver failure patient.
J Oral Maxillofac Surg. 2006; 64: 1469-1474
Oral surgery in liver transplant candidates: a retrospective study on delayed bleeding and other complications.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2016; 121: 490-495
Oral surgical treatment of patients with chronic liver disease: assessments of bleeding and its relationship with thrombocytopenia and blood coagulation parameters.
J Oral Maxillofac Surg. 2017; 75: 28-34
Normotest in the evaluation of liver function.
in: Hemker H.C. Loeliger E.A. Veltkamp J.J. Human Blood Coagulation. Human Blood Coagulation: Biochemistry, Clinical Investigation and Therapy. 1. Springer,
Berlin, Germany1969: 369-378
Oral management of the patient with end-stage liver disease and the liver transplant patient.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998; 86: 55-64
Thrombocytopenia in chronic liver disease.
Liver Int. 2017; 37: 778-793
Management of thrombocytopenia in patients with chronic liver disease.
Dig Dis Sci. 2019; 64: 2757-2768
Management of thrombocytopenia due to liver cirrhosis: a review.
World J Gastroenterol. 2014; 20: 2595-2605
Waterfall sequence for intrinsic blood clotting.
Science. 1964; 145: 1310-1312
A cell-based model of hemostasis.
Thromb Haemost. 2001; 85: 958-965
Lowering the prophylactic platelet transfusion threshold: a prospective analysis.
Leuk Lymphoma. 2001; 41: 67-76
World Workshop on Oral Medicine VII: platelet count and platelet transfusion for invasive dental procedures in thrombocytopenic patients—a systematic review.
Oral Dis. 2019; 25: 174-181
Cardiac and vascular changes in cirrhosis: pathogenic mechanisms.
World J Gastroenterol. 2006; 12: 837-842
Coagulopathy in cirrhosis: the role of the platelet in hemostasis.
J Hepatol. 2013; 59: 889-890
Coagulation, microenvironment and liver fibrosis.
Cells. 2018; 7: 85
Elevated levels of von Willebrand factor in cirrhosis support platelet adhesion despite reduced functional capacity.
Hepatology. 2006; 44: 53-61
The coagulation cascade in cirrhosis.
Clin Liver Dis. 2009; 13: 1-9
What is all that thrombin for?.
J Thromb Haemost. 2003; 1: 1504-1514
Principles and practice of thromboelastography in clinical coagulation management and transfusion practice.
Transfus Med Rev. 2012; 26: 1-13
A modified international normalized ratio as an effective way of prothrombin time standardization in hepatology.
Hepatology. 2007; 46: 528-534
Decreased prothrombin conversion and reduced thrombin inactivation explain rebalanced thrombin generation in liver cirrhosis.
PLoS One. 2017; 12e0177020
Prevention and management of bleeding risk related to invasive procedures in cirrhosis.
Semin Liver Dis. 2018; 38: 215-229
Thrombin generation assays for global evaluation of the hemostatic system: perspectives and limitations.
Rev Bras Hemato Hemoter. 2017; 39: 259-265
Alterations in fibrin structure in patients with liver diseases.
Semin Thromb Hemost. 2016; 42: 389-396
Bleeding after invasive procedures is rare and unpredicted by platelet counts in cirrhotic patients with thrombocytopenia.
Eur J Intern Med. 2017; 38: 79-82
Pre-liver transplant protocols in dentistry.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013; 115: 426-430
University of Oxford, Centre for Evidence-based Medicine. Oxford Centre for Evidence-Based Medicine: Levels of Evidence (March 2009). Available at: https://www.cebm.ox.ac.uk/resources/levels-of-evidence/oxford-centre-for-evidence-based-medicine-levels-of-evidence-march-2009. Accessed November 11, 2020.
Platelet transfusions: trigger, dose, benefits, and risks.
F1000 Med Rep. 2010; 2: 5
A review of liver transplantation for the dentist and guidelines for dental management.
Spec Care Dent. 1993; 13: 74-80