Abstract
Background
There is a movement to engage oral health care professionals in administering tests
to identify people at risk of developing contagious diseases and other medical conditions.
The purpose of this overview was to provide clinicians with fundamental concepts to
understand how to evaluate a screening test’s capability to give a correct result
and its implications for practice (health outcomes).
Types of Studies Reviewed
The authors reviewed epidemiologic and statistical articles addressing the purpose
of performing screening tests for medical conditions with a special emphasis on understanding
and interpreting test results on the basis of specific test characteristics.
Results
Tests with different sensitivities and specificities will provide different probabilities
of correctly classifying people with or without a disease of interest. By understanding
how to interpret tests results and how to communicate the consequences (that is, impact
on health outcomes) of positive and negative test results, oral health care professionals
will be able to generate appropriate medical referrals and determine the need for
further testing, as well as provide a public service.
Conclusions and Practical Implications
An understanding by oral health care professionals of how to interpret screening test
results will benefit their patients substantially and, in the case of contagious diseases,
the public at large.
Key Words
Abbreviation Key:
FN (False negative), FP (False positive), NPV (Negative predictive value), PPV (Positive predictive value), TN (True negative), TP (True positive)
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References
- Celentano D.D. Szklo M. Gordis Epidemiology. 6th ed. Elsevier,
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Diagnostic performance of an antigen test with RT-PCR for the detection of SARS-CoV-2 in a hospital setting—Los Angeles County, California, June-August 2020.
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Diagnostic accuracy of a SARS-CoV-2 rapid antigen test in real-life clinical settings.
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Biography
Dr. Glick is a professor, Department of Preventive and Restorative Sciences, and the executive director, Center for Integrative Global Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA.
Biography
Dr. Carrasco-Labra is an assistant professor, Department of Preventive and Restorative Sciences, Center for Integrative Global Oral Health, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA.
Article Info
Footnotes
Disclosures. Drs. Glick and Carrasco-Labra did not report any disclosures.
ORCID Numbers. Michael Glick: https://orcid.org/0000-0003-4236-5385; Alonso Carrasco-Labra: https://orcid.org/0000-0003-3546-3526. For information regarding ORCID numbers, go to http://orcid.org.
Identification
DOI: https://doi.org/10.1016/j.adaj.2022.01.002
Copyright
© 2022 American Dental Association. All rights reserved.
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