Abstract
Background and Overview
First bite syndrome (FBS) is an orofacial pain condition characterized by moderate
to severe unilateral facial pain associated with the first bite or taste of food.
It is important that dentists and physicians be aware of patient history and examination
findings commonly associated with FBS, as well as treatment options available for
managing this condition.
Case Description
Described here is a case of FBS arising in a 43-year-old man after partial parotidectomy
for the treatment of a mucoepidermoid carcinoma. His orofacial pain was being successfully
treated by injection of onabotulinumtoxin A into the residual parotid tissue.
Conclusions and Practical Implications
Onabotulinumtoxin A is a promising therapeutic option for FBS owing to its profound
relief of pain and minimal reported adverse effects. Therefore, oral health care providers
treating FBS should be aware of this option.
Key Words
Abbreviation Key:
ACh (Acetylcholine), BoNT-A (Onabotulinumtoxin A), FBS (First bite syndrome), NE (Norepinephrine), SNAP (Synaptosomal-associated protein), SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptor), VAS (Visual analog scale)
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Biography
Dr. Dubyk is a resident, Orofacial Pain Department, Uniformed Services University of the Health Sciences Postgraduate Dental College, Naval Medical Leader and Professional Development Command, Bethesda, MD.
Biography
Dr. Smith is the chair, Orofacial Pain Department, Uniformed Services University of the Health Sciences Postgraduate Dental College, Naval Medical Leader and Professional Development Command, Bethesda, MD.
Biography
Dr. Criddle is a faculty member, Orofacial Pain Department, Uniformed Services University of the Health Sciences Postgraduate Dental College, Naval Medical Leader and Professional Development Command.
Biography
Dr. Jones is the chair, Oral Pathology Department, Uniformed Services University of the Health Sciences Postgraduate Dental College, Naval Medical Leader and Professional Development Command, Bethesda, MD.
Biography
Dr. Hawkins is the director, Orofacial Pain Program, Uniformed Services University of the Health Sciences Postgraduate Dental College, Naval Medical Leader and Professional Development Command, 8955 Wood Rd, Bethesda, MD 20889.
Article Info
Publication History
Published online: June 15, 2021
Accepted:
April 3,
2021
Received:
March 26,
2021
Publication stage
In Press Corrected Proof
Footnotes
Disclosure. None of the authors reported any disclosures.
The views expressed in this article reflect the results of research conducted by the authors and do not necessarily reflect the official policy or position of the Department of the Navy, Department of Defense, Uniformed Services University of the Health Sciences, nor the US Government.
Identification
DOI: https://doi.org/10.1016/j.adaj.2021.04.001
Copyright
© 2021 American Dental Association. All rights reserved.
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