Home Dental Radiology Sentinel lymph node mapping of clinically N0 early oral cancer: a diagnostic pitfall on CT lymphography

Sentinel lymph node mapping of clinically N0 early oral cancer: a diagnostic pitfall on CT lymphography

by adminjay


  • 1.

    Hanai N, Asakage T, Kiyota N, Homma A, Hayashi R. Controversies in relation to neck management in N0 early oral tongue cancer. Jpn J Clin Oncol. 2019;49:297–305.

  • 2.

    Shah JP. Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract. Am J Surg. 1990;160:405–9.

  • 3.

    Byers RM, Weber RS, Andrews T, McGill D, Kare R, Wolf P. Frequency and therapeutic implications of “skip metastases” in the neck from squamous cell carcinoma of the oral tongue. Head Neck. 1997;19:14–9.

  • 4.

    Honda K, Ishiyama K, Suzuki S, Oumi E, Sato T, Kawasaki Y, et al. Sentinel lymph node biopsy using computed tomographic lymphography in patients with early tongue cancer. Acta Otolaryngol. 2015;135:507–12.

  • 5.

    Morton DL, Bostick PJ. Will the true sentinel node please stand? Ann Surg Oncol. 1999;6:12–4.

  • 6.

    Rigual N, Loree T, Frustino J, Jayaprakash V, Cohan D, Sullivan M, et al. Sentinel node biopsy in lieu of neck dissection for staging oral cancer. JAMA Otolaryngol Head Neck Surg. 2013;139:779–82.

  • 7.

    Bilde A, von Buchwald C, Therkildsen MH, Mortensen J, Kirkegaard J, Charabi B, et al. Need for intensive histopathologic analysis to determine lymph node metastases when using sentinel node biopsy in oral cancer. Laryngoscope. 2008;118:408–14.

  • 8.

    Bredell MG. Sentinel lymph node mapping by indocyanine green fluorescence imaging in oropharyngeal cancer—preliminary experience. Head Neck Oncol. 2010;2:3.

  • 9.

    Iwai T, Maegawa J, Hirota M, Tohnai I. Sentinel lymph node biopsy using a new indocyanine green fluorescence imaging system with a color charged couple device camera for oral cancer. Br J Oral Maxillofac Surg. 2013;51:e26–e2828.

  • 10.

    Miura K, Hirakawa H, Uemura H, Yoshimoto S, Shiotani A, Sugasawa M, et al. Sentinel node biopsy for oral cancer: a prospective multicenter phase II trial. Auris Nasus Larynx. 2017;44:319–26.

  • 11.

    Den Toom IJ, Heuveling DA, Flach GB, Van Weert S, Karagozoglu KH, Van Schie A, et al. Sentinel node biopsy for early oral cavity cancer: the VU University Medical Center experience. Head Neck. 2015;37:573–8.

  • 12.

    Pedersen NJ, Hebbelstrup Jensen D, Hedbäck N, Frendø M, Kiss K, et al. Staging of early lymph node metastases with the sentinel lymph node technique and predictive factors in T1/T2 oral cavity cancer: a retrospective single-center study. Head Neck. 2016;38:E1033–E10401040.

  • 13.

    den Toom IJ, van Schie A, van Weert S, Karagozoglu KH, Bloemena E, Hoekstra OS, et al. The added value of SPECT-CT for the identification of sentinel lymph nodes in early stage oral cancer. Eur J Nucl Med Mol Imaging. 2017;44:998–1004.

  • 14.

    Abdul-Razak M, Chung H, Wong E, Palme C, Veness M, Farlow D, et al. Sentinel lymph node biopsy for early oral cancers: Westmead Hospital experience. ANZ J Surg. 2017;87:65–9.

  • 15.

    Khafif A, Schneebaum S, Fliss DM, Lerman H, Metser U, Ben-Yosef R, et al. Lymphoscintigraphy for sentinel node mapping using a hybrid single photon emission CT (SPECT)/CT system in oral cavity squamous cell carcinoma. Head Neck. 2006;28:874–9.

  • 16.

    Alkureishi LW, Ross GL, Shoaib T, Soutar DS, Robertson AG, Thompson R, et al. Sentinel node biopsy in head and neck squamous cell cancer: 5-year follow-up of a European multicenter trial. Ann Surg Oncol. 2010;17:2459–64.

  • 17.

    Mokhtar M, Tadokoro Y, Nakagawa M, Morimoto M, Takechi H, Kondo K, et al. Triple assessment of sentinel lymph node metastasis in early breast cancer using preoperative CTLG, intraoperative fluorescence navigation and OSNA. Breast Cancer. 2016;23:202–10.

  • 18.

    Yamamoto S, Suga K, Maeda K, Maeda N, Yoshimura K, Oka M. Breast sentinel lymph node navigation with three-dimensional computed tomography-lymphography: a 12-year study. Breast Cancer. 2016;23:456–62.

  • 19.

    Nakagawa M, Morimoto M, Takechi H, Tadokoro Y, Tangoku A. Preoperative diagnosis of sentinel lymph node (SLN) metastasis using 3D CT lymphography (CTLG). Breast Cancer. 2016;23:519–24.

  • 20.

    Yasuta M, Sato S, Ishida T, Kiyohara T. Usefulness of CT-lymphography in sentinel lymph node navigation. Int J Clin Oncol. 2014;19:557–62.

  • 21.

    Yuasa Y, Seike J, Yoshida T, Takechi H, Yamai H, Yamamoto Y, et al. Sentinel lymph node biopsy using intraoperative indocyanine green fluorescence imaging navigated with preoperative CT lymphography for superficial esophageal cancer. Ann Surg Oncol. 2012;19:486–93.

  • 22.

    Yoshida Y, Adachi K, Nakashima K, Yamane T, Yamamoto O. Difficulty to identify sentinel lymph nodes with computed tomography-lymphography in patients with cutaneous melanoma. Acta Derm Venereol. 2011;91:465–6.

  • 23.

    Tsujimoto H, Yaguchi Y, Sakamoto N, Kumano I, Takahata R, Matsumoto Y, et al. Computed tomography lymphography for the detection of sentinel nodes in patients with gastric carcinoma. Cancer Sci. 2010;101:2586–90.

  • 24.

    Saito M, Nishiyama H, Oda Y, Shingaki S, Hayashi T. The lingual lymph node identified as a sentinel node on CT lymphography in a patient with cN0 squamous cell carcinoma of the tongue. Dentomaxillofac Radiol. 2012;41:254–8.

  • 25.

    Sugiyama S, Iwai T, Izumi T, Ishiguro K, Baba J, Oguri S, et al. CT lymphography for sentinel lymph node mapping of clinically N0 early oral cancer. Cancer Imaging. 2019;19:72.

  • 26.

    Honda K, Ishiyama K, Suzuki S, Kawasaki Y, Saito H, Horii A. Sentinel lymph node biopsy using preoperative computed tomographic lymphography and intraoperative indocyanine green fluorescence imaging in patients with localized tongue cancer. JAMA Otolaryngol Head Neck Surg. 2019;145:735–40.

  • 27.

    Mølstrøm J, Grønne M, Green A, Bakholdt V, Sørensen JA. Topographical distribution of sentinel nodes and metastases from T1–T2 oral squamous cell carcinomas. Eur J Cancer. 2019;107:86–92.

  • 28.

    Bredell MG. Sentinel lymph node mapping by indocyanine green fluorescence imaging in oropharyngeal cancer—preliminary experience. Head Neck Oncol. 2010;2:31.

  • 29.

    Peng H, Wang SJ, Niu X, Yang X, Chi C, Zhang G. Sentinel node biopsy using indocyanine green in oral/oropharyngeal cancer. World J Surg Oncol. 2015;13:278.

  • 30.

    Al-Dam A, Precht C, Barbe A, Kohlmeier C, Hanken H, Wikner J, et al. Sensitivity and specificity of sentinel lymph node biopsy in patients with oral squamous cell carcinomas using indocyanine green fluorescence imaging. J Craniomaxillofac Surg. 2018;46:1379–84.

  • 31.

    van der Vorst JR, Schaafsma BE, Verbeek FP, Keereweer S, Jansen JC, van der Velden LA, et al. Near-infrared fluorescence sentinel lymph node mapping of the oral cavity in head and neck cancer patients. Oral Oncol. 2013;49:15–9.

  • 32.

    Fang Q, Li P, Qi J, Luo R, Chen D, Zhang X. Value of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue. Laryngoscope. 2019;129:2527–30.

  • 33.

    Jia J, Jia MQ, Zou HX. Lingual lymph nodes in patients with squamous cell carcinoma of the tongue and the floor of the mouth. Head Neck. 2018;40:2383–8.

  • 34.

    Ananian SG, Gvetadze SR, Ilkaev KD, Mochalnikova VV, Zayratiants GO, Mkhitarov VA, et al. Anatomic-histologic study of the floor of the mouth: the lingual lymph nodes. Jpn J Clin Oncol. 2015;45:547–54.

  • 35.

    Ando M, Asai M, Ono T, Nakanishi Y, Asakage T, Yamasoba T. Metastases to the lingual nodes in tongue cancer: a pitfall in a conventional neck dissection. Auris Nasus Larynx. 2010;37:386–9.

  • 36.

    Ozeki S, Tashiro H, Okamoto M, Matsushima T. Metastasis to the lingual lymph node in carcinoma of the tongue. J Maxillofac Surg. 1985;13:277–81.

  • 37.

    Dutton JM, Graham SM, Hoffman HT. Metastatic cancer to the floor of mouth: the lingual lymph nodes. Head Neck. 2002;24:401–5.

  • 38.

    Umeda M, Minamikawa T, Shigeta T, Oguni A, Kataoka T, Takahashi H, et al. Metastasis to the lingual lymph node in patients with squamous cell carcinoma of the floor of the mouth: a report of two cases. Kobe J Med Sci. 2010;55:E67–72.

  • 39.

    Nishio N, Fujimoto Y, Hiramatsu M, Yamamoto Y, Sone M. Sonographic detection of a lingual node metastasis from early squamous cell cancer of the tongue. J Clin Ultrasound. 2018;46:69–72.

  • 40.

    Han W, Yang X, Huang X, Hu Q, Wang Z. Metastases to lingual lymph nodes from squamous cell carcinoma of the tongue. Br J Oral Maxillofac Surg. 2008;46:376–8.



  • Source link

    Related Articles